masterone

Absorption After oral administration, the time to reach maximum concentration (Cmax) of aliskiren in plasma is 1-3 hours and the absolute bioavailability of – 2.6%. Simultaneous eating reduces Cmax and area under the curve “concentration-time»  of aliskiren, but it does not significantly affect the pharmacodynamics of the drug. Therefore aliskiren can be used regardless of the meal.Increased  of aliskiren has a linear dependence on the dose range from 75 to 600 mg. The equilibrium concentration of aliskiren plasma levels achieved between the 5- and 7-day daily administration at one time…

Read More